21c Museum Hotel Lexington

Lexington, Kentucky

An artsy blend of quaint southern charm and big city tastes.

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Property Overview

21c Museum Hotel Lexington is a boutique hotel, contemporary art museum, cultural center, and home to the locally-sourced, chef-driven restaurant Lockbox. Woven into the fabric of downtown Lexington, 21c welcomes both visitors and the local community to enjoy the curated exhibitions and cultural programming. With more than 7,000 square feet of exhibition space and art installations gracing every corner of this property, curiosity will lead you to discover something new around every corner.


SmartFlyer Exclusives

  • Welcome amenity and drink


Agent Tips

  • Work with your SmartFlyer travel advisor to reserve a Corner King Room, featuring two full walls of near floor-to-ceiling historic windows.
  • The original vault in the building, The Safe, provides an intimate setting for private dining of small groups up to 12. The communal table just outside The Safe seats 14 and is serviced by a separate bar.
Rooms + Suites

Contemporary fun with a slight edge to it.

21c Lexington's eighty-eight guestrooms populate the historic Fayette National Bank Building, originally designed by McKim, Mead and White. The designers embraced the building's historic features to create this new space where contemporary and historic meet and contrast. With high ceilings and large historic windows, guestrooms feel residential and serve as a comfortable respite from the thought-provoking art and activity that fills the museum galleries. Outfitted with custom-designed contemporary furnishings, comfortable beds, plush robes, and Malin + Goetz bath amenities, the spaces are designed to leave you feeling refreshed and restored.
Restaurant + Bar

Bountiful Kentucky gourmet.

The menus at 21c Lexington's Lockbox showcase a commitment to the community’s craft purveyors, high-quality seasonal ingredients, and thoughtful – yet simple – cooking techniques. Lockbox‘s deep network of local providers and the bounty of ingredients fed by Kentucky’s limestone-rich soil allow the menus to change frequently. Definitely make sure to order a Temper Tantrum (or two) at Lockbox's in-house bar.
Who's it for?

A weekend refuge for all.

21c Lexington is a family-friendly stay that also serves as a weekend refuge for couples looking to escape the everyday. Between its exciting rotation of art installations and its prime location, 21c Lexington is the ideal homebase for your Bluegrass adventures.
  • Gym
    21c Lexington's 24-hour fitness center is well-equipped to fit all guests' wellness needs.
  • Location
    21c Lexington is positioned smack dab at the center of what's considered the Athens of the West, the intersection of quaint southern charm and big city tastes. This city is the jewel in the crown of the Bluegrass region.

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