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21c Museum Hotel Louisville

Louisville, Kentucky


"A unique stay that blends Southern charm with tasteful modern eccentrics."

City Family Culture

21c Louisville is a boutique hotel, contemporary art museum, and award-winning restaurant all under one roof in the heart of downtown Louisville. Here, guests are treated to a property that immerses guests in the art it houses. Dine next to breathtaking pieces of art, walk beneath vivid installations, or sleep in Asleep in the Cyclone, a multicolored site-specific installation that doubles as a guest room. And when you’re ready, step right outside to a plethora of dining and entertainment options within walking distance.


Swanky, provocative and chic, with art around every corner.

Erin Trager-Kusman
Rooms + Suites

All the room types are unique and there isn’t a bad option. The deluxe rooms have a view of the building, which is surprisingly interesting and beautiful. The suites are all unique, and great for families or extended stays (I’d recommend one of the three corner suites, which can also connect to a luxury king if needed). Balcony rooms are a no-brainer in the nicer months with equal amount of outdoor space as indoor. Of course, there is the Cyclone Room for an immersive 21c art experience. Last but not least The Penthouse apartment, which is absolutely stunning with a kitchen and living room, and a large outdoor terrace. The Penthouse can also be used for private events for up to seventy-five people.

Erin Trager-Kusman

21c Louisville’s 24-hour fitness center is available to all guests and offers yoga classes in the museum galleries.


The 21c spa located within the fitness center contains a sauna and steam room available for guest use 24 hours. There are also two massage rooms where you can take advantage of their aromatherapy and reflexology massage treatments.


21c Louisville’s on-site restaurant Proof on Main is a destination for foodies and bourbon-enthusiasts, as well as a local hotspot. Proof’s soulful, ingredient driven menu is a showcase for the bounty of the Ohio River: fresh, local, and seasonal ingredients inspire the ever-evolving menu. What cannot be used immediately is pickled or preserved and saved. In addition to partnerships with regional farmers and producers, Proof on Main’s unique relationship with Woodland Farm allows diners to eat locally raised heritage meats and to sample the season’s best produce.


The bar here is one of the best in town – very swanky and chic, with seasonal cocktails and of course, Bourbon. I recommend grabbing a drink and walking through the gallery before dinner (or any time, really) – one of my favorite things to do in town. Take take home one of their 21c Selects – barrel selections from our team bottled exclusively for 21c and Proof on Main.

Erin Trager-Kusman
Who's it for?

21c Louisville is a great fit for couples and families alike. Couples can enjoy a romantic getaway within a unique art-filled space while families (including those with pets in tow) are provided a comfy home base that’s just steps away from an exciting, event-filled neighborhood.


21c Louisville is located in downtown's historic Museum Row neighboring museums and cultural attractions, along with dining and entertainment venues. Highlights include the Urban Bourbon Train, Louisville Slugger Museum, Kentucky Museum of Art and Craft, Muhammad Ali Center, KFC Yum! Center, and the nearby Nulu neighborhood including art galleries and shopping.

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Agent's Tips

Go with the Luxury Suite for natural light with tall triple-paned windows (with plenty of heavy soundproofing to ensure a perfect night's sleep)!

For a luxury experience like no other, work with your SmartFlyer travel advisor to gain access to the owners' exclusive "private side" of the Rooftop Apartment: a two-bedroom space for VVIPs and guests with special requirements.

SmartFlyer Exclusives

Welcome note and bourbon chocolate set

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